Research

ARDS

Mechanical Ventilation for Acute Respiratory Distress Syndrome during Extracorporeal Life Support. Research and Practice
Abrams D, Schmidt M, Pham T, Beitler JR, Fan E, Goligher EC, McNamee JJ, Patroniti N, Wilcox ME, Combes A, Ferguson ND, McAuley DF, Pesenti A, Quintel M, Fraser J, Hodgson CL, Hough CL, Mercat A, Mueller T, Pellegrino V, Ranieri VM, Rowan K, Shekar K, Brochard L, Brodie D. Mechanical Ventilation for Acute Respiratory Distress Syndrome during Extracorporeal Life Support. Research and Practice. Am J Respir Crit Care Med. 2020 Mar 1;201(5):514-525. doi: 10.1164/rccm.201907-1283CI. PMID: 31726013.

ECMO for ARDS: from salvage to standard of care?
Abrams D, Ferguson ND, Brochard L, Fan E, Mercat A, Combes A, Pellegrino V, Schmidt M, Slutsky AS, Brodie D. ECMO for ARDS: from salvage to standard of care? Lancet Respir Med. 2019 Feb;7(2):108-110. doi: 10.1016/S2213-2600(18)30506-X. Epub 2019 Jan 11. Erratum in: Lancet Respir Med. 2019 Feb;7(2):e9. PMID: 30642778.

Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome
Combes A, Hajage D, Capellier G, Demoule A, Lavoué S, Guervilly C, Da Silva D, Zafrani L, Tirot P, Veber B, Maury E, Levy B, Cohen Y, Richard C, Kalfon P, Bouadma L, Mehdaoui H, Beduneau G, Lebreton G, Brochard L, Ferguson ND, Fan E, Slutsky AS, Brodie D, Mercat A; EOLIA Trial Group, REVA, and ECMONet. Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome. N Engl J Med. 2018 May 24;378(21):1965-1975. doi: 10.1056/NEJMoa1800385. PMID: 29791822.

Bridge to Transplant or Recovery

ECMO as a Bridge to Left Ventricular Assist Device or Heart Transplantation - ClinicalKey
Ersilia M. DeFilippis, Kevin Clerkin, Lauren K. Truby, Michael Francke, Justin Fried, Amirali Masoumi, A. Reshad Garan, Maryjane A. Farr, Hiroo Takayama, Koji Takeda, Nir Uriel, Veli K. Topkara. ECMO as a Bridge to Left Ventricular Assist Device or Heart Transplantation,JACC: Heart Failure,Volume 9, Issue 4,2021,Pages 281-289,ISSN 2213-1779. https://doi.org/10.1016/j.jchf.2020.12.012
(https://www.sciencedirect.com/science/article/pii/S2213177921000123)

Lung transplantation disparities based on diagnosis for patients bridging to transplant on extracorporeal membrane oxygenation - PubMed (nih.gov)
Furfaro, D., Rosenzweig, E. B., Shah, L., Robbins, H., Anderson, M., Kim, H., Abrams, D., Agerstrand, C. L., Brodie, D., Feldhaus, D., Costa, J., Lemaitre, P., Stanifer, B. P., D'Ovidio, F., Sonett, J. R., Arcasoy, S., & Benvenuto, L. (2021). Lung transplantation disparities based on diagnosis for patients bridging to transplant on extracorporeal membrane oxygenation. The Journal of heart and lung transplantation: the official publication of the International Society for Heart Transplantation, 40(12), 1641–1648. 

Outcomes of Extracorporeal Membrane Oxygenation as a Bridge to Lung Transplantation
Tipograf Y, Salna M, Minko E, Grogan EL, Agerstrand C, Sonett J, Brodie D, Bacchetta M. Outcomes of Extracorporeal Membrane Oxygenation as a Bridge to Lung Transplantation. Ann Thorac Surg. 2019 May;107(5):1456-1463. doi: 10.1016/j.athoracsur.2019.01.032. Epub 2019 Feb 18. PMID: 30790550.

Midterm Outcomes of Bridge-to-Recovery Patients After Short-Term Mechanical Circulatory Support
Cheng YT, Garan AR, Sanchez J, Kurlansky P, Ando M, Cevasco M, Yuzefpolskaya M, Colombo PC, Naka Y, Takayama H, Takeda K. Midterm Outcomes of Bridge-to-Recovery Patients After Short-Term Mechanical Circulatory Support. Ann Thorac Surg. 2019 Aug;108(2):524-530. doi: 10.1016/j.athoracsur.2019.01.060. Epub 2019 Mar 6. PMID: 30851259.

Cardiac Arrest

Ten-year outcomes of extracorporeal life support for in-hospital cardiac arrest at a tertiary center.
Salna, M., Sanchez, J., Fried, J. et al. Ten-year outcomes of extracorporeal life support for in-hospital cardiac arrest at a tertiary center. J Artif Organs 23, 321–327 (2020). https://doi.org/10.1007/s10047-020-01217-5

Cardiogenic Shock

Sex differences in patients with cardiogenic shock requiring extracorporeal membrane oxygenation
Wang A.S., Nemeth S., Kurlansky P., Brodie D., Takayama H., Naka Y., Kaku Y., (...), Takeda K.
(2022)  Journal of Thoracic and Cardiovascular Surgery,  164  (3) , pp. 960-969.e6.

Early venoarterial extracorporeal membrane oxygenation improves outcomes in post-cardiotomy shock
Saha, A., Kurlansky, P., Ning, Y. et al. Early venoarterial extracorporeal membrane oxygenation improves outcomes in post-cardiotomy shock. J Artif Organs 24, 7–14 (2021). https://doi.org/10.1007/s10047-020-01212-w

Venoarterial extracorporeal membrane oxygenation to rescue sepsis-induced cardiogenic shock: a retrospective, multicentre, international cohort study
Bréchot N, Hajage D, Kimmoun A, Demiselle J, Agerstrand C, Montero S, Schmidt M, Luyt CE, Lebreton G, Hékimian G, Flecher E, Zogheib E, Levy B, Slutsky AS, Brodie D, Asfar P, Combes A; International ECMO Network. Venoarterial extracorporeal membrane oxygenation to rescue sepsis-induced cardiogenic shock: a retrospective, multicentre, international cohort study. Lancet. 2020 Aug 22;396(10250):545-552. doi: 10.1016/S0140-6736(20)30733-9. PMID: 32828186.

Temporary circulatory support for cardiogenic shock
Combes A, Price S, Slutsky AS, Brodie D. Temporary circulatory support for cardiogenic shock. Lancet. 2020 Jul 18;396(10245):199-212. doi: 10.1016/S0140-6736(20)31047-3. PMID: 32682486.

Prospective Comparison of a Percutaneous Ventricular Assist Device and Venoarterial Extracorporeal Membrane Oxygenation for Patients With Cardiogenic Shock Following Acute Myocardial Infarction
Garan AR, Takeda K, Salna M, Vandenberge J, Doshi D, Karmpaliotis D, Kirtane AJ, Takayama H, Kurlansky P. Prospective Comparison of a Percutaneous Ventricular Assist Device and Venoarterial Extracorporeal Membrane Oxygenation for Patients With Cardiogenic Shock Following Acute Myocardial Infarction. J Am Heart Assoc. 2019 May 7;8(9):e012171. doi: 10.1161/JAHA.119.012171. PMID: 31041870; PMCID: PMC6512118.

Left Ventricular Unloading During Extracorporeal Membrane Oxygenation in Patients With Cardiogenic Shock
Russo JJ, Aleksova N, Pitcher I, Couture E, Parlow S, Faraz M, Visintini S, Simard T, Di Santo P, Mathew R, So DY, Takeda K, Garan AR, Karmpaliotis D, Takayama H, Kirtane AJ, Hibbert B. Left Ventricular Unloading During Extracorporeal Membrane Oxygenation in Patients With Cardiogenic Shock. J Am Coll Cardiol. 2019 Feb 19;73(6):654-662. doi: 10.1016/j.jacc.2018.10.085. PMID: 30765031.

Novel minimally invasive surgical approach using an external ventricular assist device and extracorporeal membrane oxygenation in refractory cardiogenic shock | European Journal of Cardio-Thoracic Surgery | Oxford Academic (oup.com)
Koji Takeda, Arthur R. Garan, Veli K. Topkara, Ajay J. Kirtane, Dimitri Karmpaliotis, Paul Kurlansky, Melana Yuzefpolskaya, Paolo C. Colombo, Yoshifumi Naka, Hiroo Takayama, Novel minimally invasive surgical approach using an external ventricular assist device and extracorporeal membrane oxygenation in refractory cardiogenic shock, European Journal of Cardio-Thoracic Surgery, Volume 51, Issue 3, March 2017, Pages 591–596, https://doi.org/10.1093/ejcts/ezw349

Lu DY, Adelsheimer A, Chan K, Yeo I, Krishnan U, Karas MG, Horn EM, Feldman DN, Sobol I, Goyal P, Bhatt R, Batra S, Sciria CT, Olonoff D, Cheung JW, Kim LK. Impact of hospital transfer to hubs on outcomes of cardiogenic shock in the real world. Eur J Heart Fail. 2021 Nov;23(11):1927-1937.

Adelsheimer A, Wang J, Lu DY, Elbaum L, Krishnan U, Cheung JW, Feldman DN, Wong SC, Horn EM, Sobol I, Goyal P, Karas MG, Kim LK. Impact of Socioeconomic Status on Mechanical Circulatory Device Utilization and Outcomes in Cardiogenic Shock. Journal of the Society for Cardiovascular Angiography & Interventions. 2022. https://doi.org/10.1016/j.jscai.2022.100027.

Wang JI, Lu DY, Feldman DN, McCullough SA, Goyal P, Karas MG, Sobol I, Horn EM, Kim LK, Krishnan U. Outcomes of Hospitalizations for Cardiogenic Shock at Left Ventricular Assist Device Versus Non-Left Ventricular Assist Device Centers. J Am Heart Assoc. 2020;9(23): e017326. https://doi.org/10.1161/JAHA.120.017326.

Hospital market concentration and the use of mechanical circulatory support devices in acute myocardial infarction complicated by cardiogenic shock.
Vohra AS, Jang SJ, Feldman DN, Goyal P, Krishnan U, Sciria C, Cheung JW, Kim LK.BMC Health Serv Res. 2022 Jan 19;22(1):89. doi: 10.1186/s12913-021-07458-1.

Characteristics of hospitalizations for cardiogenic shock after acute myocardial infarction in the United States.
Krishnan U, Brejt JA, Schulman-Marcus J, Swaminathan RV, Feldman DN, Chiu Wong S, Goyal P, Horn EM, Karas M, Sobol I, Minutello RM, Bergman G, Singh H, Kim LK.Int J Cardiol. 2017 Oct 1;244:213-219. doi: 10.1016/j.ijcard.2017.06.088. Epub 2017 Jun 27.PMID: 28676243

COVID-19

Extracorporeal membrane oxygenation for COVID-19: evolving outcomes from the international Extracorporeal Life Support Organization Registry - PubMed (nih.gov)
Barbaro, R. P., MacLaren, G., Boonstra, P. S., Combes, A., Agerstrand, C., Annich, G., Diaz, R., Fan, E., Hryniewicz, K., Lorusso, R., Paden, M. L., Stead, C. M., Swol, J., Iwashyna, T. J., Slutsky, A. S., Brodie, D., & Extracorporeal Life Support Organization (2021). Extracorporeal membrane oxygenation for COVID-19: evolving outcomes from the international Extracorporeal Life Support Organization Registry. Lancet (London, England), 398(10307), 1230–1238

Extracorporeal Membrane Oxygenation for Coronavirus Disease 2019: Crisis Standards of Care - PubMed (nih.gov)
Agerstrand, C., Dubois, R., Takeda, K., Uriel, N., Lemaitre, P., Fried, J., Masoumi, A., Cheung, E. W., Kaku, Y., Witer, L., Liou, P., Gerall, C., Klein-Cloud, R., Abrams, D., Cunningham, J., Madahar, P., Parekh, M., Short, B., Yip, N. H., Serra, A., … Brodie, D. (2021). Extracorporeal Membrane Oxygenation for Coronavirus Disease 2019: Crisis Standards of Care. ASAIO journal (American Society for Artificial Internal Organs : 1992), 67(3), 245–249. 

Extracorporeal membrane oxygenation support in COVID-19: an international cohort study of the Extracorporeal Life Support Organization registry
Barbaro RP, MacLaren G, Boonstra PS, Iwashyna TJ, Slutsky AS, Fan E, Bartlett RH, Tonna JE, Hyslop R, Fanning JJ, Rycus PT, Hyer SJ, Anders MM, Agerstrand CL, Hryniewicz K, Diaz R, Lorusso R, Combes A, Brodie D; Extracorporeal Life Support Organization. Extracorporeal membrane oxygenation support in COVID-19: an international cohort study of the Extracorporeal Life Support Organization registry. Lancet. 2020 Oct 10;396(10257):1071-1078. doi: 10.1016/S0140-6736(20)32008-0. Epub 2020 Sep 25. Erratum in: Lancet. 2020 Oct 10;396(10257):1070. PMID: 32987008; PMCID: PMC7518880.

Preparing for the Most Critically Ill Patients With COVID-19: The Potential Role of Extracorporeal Membrane Oxygenation
MacLaren G, Fisher D, Brodie D. Preparing for the Most Critically Ill Patients With COVID-19: The Potential Role of Extracorporeal Membrane Oxygenation. JAMA. 2020 Apr 7;323(13):1245-1246. doi: 10.1001/jama.2020.2342. PMID: 32074258.

Early Mobilization

Early Mobilization during Extracorporeal Membrane Oxygenation for Cardiopulmonary Failure in Adults: Factors Associated with Intensity of Treatment - PubMed (nih.gov)
Abrams, D., Madahar, P., Eckhardt, C. M., Short, B., Yip, N. H., Parekh, M., Serra, A., Dubois, R. L., Saleem, D., Agerstrand, C., Scala, P., Benvenuto, L., Arcasoy, S. M., Sonett, J. R., Takeda, K., Meier, A., Beck, J., Ryan, P., Fan, E., Hodgson, C. L., … MORE-PT Investigators (2022). Early Mobilization during Extracorporeal Membrane Oxygenation for Cardiopulmonary Failure in Adults: Factors Associated with Intensity of Treatment. Annals of the American Thoracic Society, 19(1), 90–98. 

ECMO Weaning

How I approach weaning from venoarterial ECMO - PMC (nih.gov)
Fried JA, Masoumi A, Takeda K, Brodie D. How I approach weaning from venoarterial ECMO. Crit Care. 2020 Jun 8;24(1):307. doi: 10.1186/s13054-020-03010-5. PMID: 32513218; PMCID: PMC7278069.

Interfacility ECMO Transport

A decade of interfacility extracorporeal membrane oxygenation transport
Tipograf Y, Liou P, Oommen R, Agerstrand C, Abrams D, Brodie D, Bacchetta M. A decade of interfacility extracorporeal membrane oxygenation transport. J Thorac Cardiovasc Surg. 2019 Apr;157(4):1696-1706. doi: 10.1016/j.jtcvs.2018.09.139. Epub 2018 Nov 29. PMID: 30655061.

Lung Protection

Risks and Benefits of Ultra-Lung-Protective Invasive Mechanical Ventilation Strategies with a Focus on Extracorporeal Support - PubMed (nih.gov)
Abrams, D., Agerstrand, C., Beitler, J. R., Karagiannidis, C., Madahar, P., Yip, N. H., Pesenti, A., Slutsky, A. S., Brochard, L., & Brodie, D. (2022). Risks and Benefits of Ultra-Lung-Protective Invasive Mechanical Ventilation Strategies with a Focus on Extracorporeal Support. American journal of respiratory and critical care medicine, 205(8), 873–882.

Palliative Care and Withdrawal of ECMO

The Role of Palliative Care in Withdrawal of Venoarterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock
Godfrey S, Sahoo A, Sanchez J, Fried J, Masoumi A, Brodie D, Takayama H, Uriel N, Takeda K, Nakagawa S. The Role of Palliative Care in Withdrawal of Venoarterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock. J Pain Symptom Manage. 2020 Nov 1:S0885-3924(20)30856-3. doi: 10.1016/j.jpainsymman.2020.10.027. Epub ahead of print. PMID: 33137423.

Pulmonary Hypertension

Extracorporeal life support bridge for pulmonary hypertension: A high-volume single-center experience
Rosenzweig EB, Gannon WD, Madahar P, Agerstrand C, Abrams D, Liou P, Brodie D, Bacchetta M. Extracorporeal life support bridge for pulmonary hypertension: A high-volume single-center experience. J Heart Lung Transplant. 2019 Dec;38(12):1275-1285. doi: 10.1016/j.healun.2019.09.004. Epub 2019 Sep 12. PMID: 31582284.

Quality Improvement 

ECMO During a Pandemic: A COVID-19 Quality Improvement Process
Monika Tukacs, Darshani Singh, Catherine A. Halliday; ECMO During a Pandemic: A COVID-19 Quality Improvement Process. AACN Adv Crit Care 15 September 2021; 32 (3): 247–263.

Respiratory Failure

Extracorporeal Life Support for Adults With Respiratory Failure and Related Indications: A Review
Brodie D, Slutsky AS, Combes A. Extracorporeal Life Support for Adults With Respiratory Failure and Related Indications: A Review. JAMA. 2019 Aug 13;322(6):557-568. doi: 10.1001/jama.2019.9302. PMID: 31408142.

Status Asthmaticus

Extracorporeal Carbon Dioxide Removal in the Treatment of Status Asthmaticus
Bromberger BJ, Agerstrand C, Abrams D, Serra A, Apsel D, Tipograf Y, Ginsburg ME, Ebright MI, Stanifer BP, Oommen R, Bacchetta M, Brodie D, Sonett JR. Extracorporeal Carbon Dioxide Removal in the Treatment of Status Asthmaticus. Crit Care Med. 2020 Oct 7. doi: 10.1097/CCM.0000000000004645. Epub ahead of print. PMID: 33031151.

V-A ECMO

Left ventricular distension and venting strategies for patients on venoarterial extracorporeal membrane oxygenation - Cevasco - Journal of Thoracic Disease (amegroups.com)
Cevasco, Marisa, Hiroo Takayama, Masahiko Ando, Arthur R. Garan, Yoshifumi Naka, & Koji Takeda. "Left ventricular distension and venting strategies for patients on venoarterial extracorporeal membrane oxygenation." Journal of Thoracic Disease [Online], 11.4 (2019): 1676-1683. Web. 30 Aug. 2022