Find A Physician

Return to Blood Cancer Overview

More on Blood Cancer

Hospital News

Return to Blood Cancer Overview

More on Blood Cancer

Research and Clinical Trials

Return to Blood Cancer Overview

More on Blood Cancer

Blood Cancer

The NewYork-Presbyterian Cancer Centers offer comprehensive programs in the diagnosis and treatment of hematological malignancies, with oncology specialists in lymphoma and multiple myeloma, as well as various types of leukemias and myelodysplastic syndromes. Patients benefit from the programs and resources offered at both NewYork-Presbyterian Hospital/Columbia University Medical Center and NewYork-Presbyterian Hospital/Weill Cornell Medical Center, including state-of-the-art treatment protocols involving new therapeutic agents derived from the Centers' major investment in basic and clinical research.

Diagnostic Innovations

Decisions about treatment involve the Hospital's world-class diagnostic services, which incorporate the fields of hematology, pathology, molecular biology, immunology, radiology, and nuclear medicine. The diagnostic pathology group of NewYork-Presbyterian Cancer Centers is widely regarded as among the world's best group of hematopathologists, particularly in the area of lymphoma.

Therapeutic Excellence

Advances in the treatment of hematological cancers are the result of integrated teamwork among many oncology specialists at NewYork-Presbyterian Cancer Centers. The Centers' physicians are committed to reducing toxicity related to treatments, and making sure that patients have access to all major therapeutic options, including chemotherapy, radiation therapy, monoclonal antibody therapy, and autologous and allogeneic blood and marrow transplantation.

Vaccine Therapies

Through its Cellular Immunotherapy Research Laboratory, NewYork-Presbyterian/Columbia is exploring vaccine therapies for treating a number of different hematological malignancies. The vaccine therapy is administered after a patient has had a transplant and completed a chemotherapy regimen. The goal is to trigger an immune response that will destroy any remaining malignancy. NewYork-Presbyterian/Weill Cornell is a leading institution in the development of vaccines immunotherapies. Calling on the body's own immune cells and antibodies to fight the cancers, these therapies use a particular antigen (target) derived from the cancer cell, or work by creating genetic material for the cell that will attract an immune response. These immune system vaccines show great promise in fighting cancers and preventing recurrence. For lymphoma, the Medical Center also is a leading center in a Phase III clinical trial that may establish the ultimate clinical benefit for these techniques.

Genetics

Many approaches to genetic treatment of hematological cancers are being examined, including the use of antisense agents. These agents are designed to block the "instructions" inside a cell that result in its malignant growth.

Single and Combination Therapies for Hematological Malignancy At NewYork-Presbyterian/Columbia, a comprehensive program for hematological malignancies includes individualized chemotherapy treatments, innovative antibody and small molecule clinical trials, and an integrated stem cell transplantation program. The expertise of its physicians has led NewYork-Presbyterian/Columbia to be named a National Center for Excellence in myelodysplastic syndromes and leukemia. One area of investigation includes the use of chemotherapy and antibody combinations for treatment of leukemias and lymphomas in an attempt to minimize toxic effects of treatment and take advantage of combined clinical efficacy against tumors. Excellent results have been achieved in treating patients with chronic lymphocytic leukemia, low-grade lymphomas, and Waldenstrom's macroglobulinemia. A trial for patients with relapsed leukemia and myelodysplastic syndromes is in progress using a new antibody/chemotherapy combination.

Drug Therapies

A greater understanding of the biology of blood and lymphatic cancers has given rise to more precisely calibrated combinations of drug therapies or combinations of drug and radiation therapies, which may achieve improved outcomes for patients. The strength of the leukemia programs at both NewYork-Presbyterian/Weill Cornell and NewYork-Presbyterian/Columbia has led to their collaboration in a major multi-institutional National Cancer Institute-sponsored research protocol for relapsed leukemias using bryostatin, a chemotherapy-enhancing agent. Small molecules, developed at NewYork-Presbyterian/Columbia, now are available for use in clinical trials with chemotherapy for myeloma, chronic leukemias, and lymphomas. NewYork-Presbyterian/Weill Cornell has been a leading site for the development of Gleevec, a new type of treatment for chronic myelogenous leukemia that now is a standard treatment for the disease. More than 40 different drugs now are being used in the treatment of hematological diseases, and drug development efforts at the Hospital are evaluating scores of new agents that ultimately may impact treatment outcomes for cancer patients.

  • Bookmark
  • Print





Top of page