Our researchers in pediatric infectious diseases and basic virology are bridging clinical pediatrics and basic research in the development of a disease, or pathogenesis. Our infectious diseases research team, led by Dr. Anne Moscona, is focusing on the molecular pathogenesis of human paramyxoviruses – a group of viruses responsible for many respiratory diseases – including parainfluenza virus type 3 and the emerging pathogen Hendra virus. Parainfluenza virus is an important cause of lower respiratory tract infections in children, including croup and bronchiolitis. There are currently no vaccines or antiviral agents for these diseases. Hendra virus is a highly fatal paramyxovirus that is a potential agent of bioterrorism. Dr. Moscona is studying how these viruses enter cells by fusing with the cells’ membranes and walls, and how scientists might interfere with this viral entry process. Both the parainfluenza and Hendra projects are funded by investigator-initiated NIH grants.
Patricia DeLaMora, MD Antibiotic Testing, Bacterial Infection, Bone and Joint Infections, Infectious Disease, Lyme Disease, Sinusitis, Tonsillitis, Viral Infection, Fever
Anne Moscona, MD Influenza, H1N1, Hendra Virus, Global Health, Travel Health, Vaccination, Respiratory Infection, Viral Infection
Christine Salvatore, MD Opportunistic Infection, Respiratory Infection, Infectious Disease In Immune Disorders, Pediatric HIV, Fungal Infection, Bacterial Infection, HIV, Mycoplasma Pneumonia
Sima S. Toussi, MD HIV/AIDS, Opportunistic Infection, Bone and Joint Infections
Matteo Porotto, PhD Hendra Virus, Human Parainfluenza, Viral Infection