Obesity Research 

Please contact the Division of Pediatric Endocrinology at Weill Cornell Medical College(212-746-3975) for more information about these studies.

  1. Continuous Glucose Monitoring in Obese Children and Adolescents. This study, sponsored in part by Medtronic Inc, is for obese children, adolescents, and young adults ages 4-25 years. The study objective is to analyze MAGE (mean amplitude of glycemic excursions) by using a 3 day, continuous blinded sensor. MAGE values are not known or described in obese and at risk adolescents and children, but high MAGE values are well described risk factors for diabetes related complications in adults.

  2. Urinary PGE-M and Pediatric Obesity. This study seeks to determine if elevated BMI is associated with increased urinary PGE-M, a marker of inflammation, in an otherwise healthy pediatric population.

  3. WelKid. Industry sponsored clinical trial for children and adolescents ages 10 - 17 years of age with type 2 diabetes. The study's goal is to test the effectiveness of Colesevelam (Welchol (R) ), a medication already approved in adults with T2DM, in the pediatric age group with type 2 diabetes mellitus. The trial duration is one year.

  4. GAIT study. This study is led by principal investigator Dr. Howard Hillstrom from The Hospital for Special Surgery and aims to study joint stress and joint mechanics in obese children ages 13-16 years. The study involves a history and examination, fasting bloodwork to assess for markers of systemic and joint inflammation, and a brief period of exercise while simultaneously wearing sensors and pressure meters on joints analyzed via video motion sensor analysis.

  5. DANCE study. This study has completed and results have been published, but we are currently considering a continuation of the original trial. This 6 week after school dance study aimed to recruit children from grades 4 and 5 to dance one hour a day, 4 days a week, for 6 weeks as a way to have them be active, achieve cardiometabolic fitness, and lose weight in the process. The study was strongly supported by the Cornell Cooperative Group.

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