Glossary of Medical Terms

IDEC-Y2B8

A radiolabeled monoclonal antibody that is used to treat certain types of B-cell non-Hodgkin lymphoma and is being studied in the treatment of other types of B-cell tumors. It is made up of the monoclonal antibody ibritumomab plus the radioisotope yttrium Y 90. It binds to the protein called CD20, which is found on B cells. The radiation in the yttrium Y 90 may kill the cancer cells. IDEC-Y2B8 is a type of radiopharmaceutical. Also called Y 90 ibritumomab tiuxetan, Y 90 Zevalin, and yttrium Y 90 ibritumomab tiuxetan.

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